San Diego, CA

Looking for the best smoke shop in San Diego, California? Here are the top 10 smoke and vape shops in San Diego, ranked by Google rating and review count — with addresses, a map, and directions.

1. 1

   Exclusive Smoke Shop - CBD and Vape Store San Diego

   3539 Adams Ave, San Diego, CA 92116, USA

   ★ 5.0(1,887 reviews)Claim this listingView on Google MapsDirections →
2. 2

   Mission Valley Smoke Shop and Cigars

   10459 San Diego Mission Rd, San Diego, CA 92108, USA

   ★ 5.0(1,017 reviews)Claim this listingView on Google MapsDirections →
3. 3

   San Diego Vapes Smoke Shop

   610 University Ave, San Diego, CA 92103, USA

   ★ 5.0(951 reviews)Claim this listingView on Google MapsDirections →
4. 4

   Vape Smoke Universe #1

   7190 Miramar Rd E115, San Diego, CA 92121, USA

   ★ 4.8(1,122 reviews)Claim this listingView on Google MapsDirections →
5. 5

   Leyla's Smoke & Vape

   32 25th St, San Diego, CA 92102, USA

   ★ 5.0(802 reviews)Claim this listingView on Google MapsDirections →
6. 6

   The Cage Smoke Shop

   3069 El Cajon Blvd, San Diego, CA 92104, USA

   ★ 4.8(683 reviews)Claim this listingWebsiteView on Google MapsDirections →
7. 7

   Golden Hill Smoke Shop & Cigars

   1036 25th St, San Diego, CA 92102, USA

   ★ 5.0(501 reviews)Claim this listingView on Google MapsDirections →
8. 8

   Little Italy Smoke & Vape

   1835 Columbia St, San Diego, CA 92101, USA

   ★ 5.0(472 reviews)Claim this listingWebsiteView on Google MapsDirections →
9. 9

   25th Smoke and Vape

   2479 Broadway, San Diego, CA 92102, USA

   ★ 5.0(382 reviews)Claim this listingWebsiteView on Google MapsDirections →
10. 10

    Red Eye Smoke & Vape Shop

    5061 Federal Blvd, San Diego, CA 92102, USA

    ★ 4.9(429 reviews)Claim this listingView on Google MapsDirections →

Ratings and reviews from Google Maps. Updated October 16, 2026.