St. Charles, MO

Looking for the best smoke shop in St. Charles, Missouri? Here are the top 10 smoke and vape shops in St. Charles, ranked by Google rating and review count — with addresses, a map, and directions.

1. 1

   Mr. Nice Guy St. Charles

   1560 Veterans Memorial Pkwy, St Charles, MO 63303, USA

   ★ 4.8(1,566 reviews)Claim this listingWebsiteView on Google MapsDirections →
2. 2

   Greatest Shop Ever

   1125 Cave Springs Blvd, St Peters, MO 63376, USA

   ★ 4.7(1,498 reviews)Claim this listingView on Google MapsDirections →
3. 3

   STUDIO 420

   1881 Sherman Dr, St Charles, MO 63303, USA

   ★ 4.7(1,257 reviews)Claim this listingWebsiteView on Google MapsDirections →
4. 4

   Root 66 Dispensary - St. Peters, MO

   3004 S St Peters Pkwy, St Charles, MO 63303, USA

   ★ 4.6(782 reviews)Claim this listingWebsiteView on Google MapsDirections →
5. 5

   Black Sheep Smokeshop

   2975 N St Peters Pkwy, St Peters, MO 63376, USA

   ★ 5.0(367 reviews)Claim this listingWebsiteView on Google MapsDirections →
6. 6

   Spark Tobacco & Vape

   2244 1st Capitol Dr, St Charles, MO 63301, USA

   ★ 5.0(220 reviews)Claim this listingView on Google MapsDirections →
7. 7

   Discount Smoke Shop

   1476 South Dr, St Charles, MO 63303, USA

   ★ 4.4(358 reviews)Claim this listingWebsiteView on Google MapsDirections →
8. 8

   Nirvana Smoke and Snacks

   4235 N St Peters Pkwy, St Peters, MO 63304, USA

   ★ 4.9(151 reviews)Claim this listingWebsiteView on Google MapsDirections →
9. 9

   Puff360 Smoke Shop

   2305 Droste Rd, St Charles, MO 63301, USA

   ★ 4.9(125 reviews)Claim this listingView on Google MapsDirections →
10. 10

    710 Glass Co. St. Charles

    3104 W Clay St, St Charles, MO 63301, USA

    ★ 4.6(129 reviews)Claim this listingWebsiteView on Google MapsDirections →

Ratings and reviews from Google Maps. Updated October 16, 2026.